• Pediatr Crit Care Me · Apr 2023

    Single-Center Experience Using the Cardiohelp System for Neonatal and Pediatric Extracorporeal Membrane Oxygenation.

    • Nisha Agasthya, Curtis D Froehlich, Michael Golecki, Marisa Meyer, Mark T Ogino, Kendra Froehlich, Christopher Beaty, Sharon McCants, Timothy M Maul, and Daniel R Dirnberger.
    • Department of Pediatrics, Kansas University School of Medicine, Wichita, KS.
    • Pediatr Crit Care Me. 2023 Apr 1; 24 (4): e190e195e190-e195.

    ObjectivesExtracorporeal membrane oxygenation (ECMO) systems have continued to evolve and improve with the development of smaller and portable systems. The Cardiohelp (Maquet Getinge Cardiopulmonary AG, Rastatt, Germany) portable life support device is a compact ECMO system used widely in adults and for ECMO transport. Reports of its use in neonatal and pediatric centers remain limited. In this single-center retrospective review, we describe our institutional experience with the Cardiohelp.DesignSingle-center retrospective review.SettingNeonatal ICUs and PICUs in a tertiary-care children's hospital.PatientsSeventeen pediatric patients on ECMO.InterventionsNone.Measurements And Main ResultsMedian (interquartile range, IQR) of patient age was 0.5 years (0-7 yr). Eleven of 17 patients were on veno-arterial ECMO, five on veno-venous ECMO, and one on veno-venoarterial ECMO. All veno-venous and veno-venoarterial runs ( n = 6) were accomplished with bicaval, dual-lumen cannulae. Median duration on Cardiohelp was 113 hours (IQR 50-140 hr). Median anti-Xa level for patients was 0.43 IU/mL (IQR 0.35-0.47 IU/mL), with median heparin dose of 23.6 U/kg/hr (IQR 17.6-28.1 U/kg/hr). Median plasma-free hemoglobin was 41.4 mg/dL (IQR 30-60 mg/dL). Circuit change was required in three cases. Fourteen patients survived ECMO, with 13 patients surviving to discharge.ConclusionsWe have used the Cardiohelp system to support 17 neonatal and pediatric ECMO patients, without complications. Further studies are warranted to compare complications, outcomes, and overall cost with other institutions and other existing ECMO systems.Copyright © 2022 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

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