• J Clin Apher · Dec 2006

    Case Reports

    Combination regimen of methylprednisolone, IV immunoglobulin, and plasmapheresis early in the treatment of acute disseminated encephalomyelitis.

    • Rommel P Lu and Gary Keilson.
    • Department of Medicine, Saint Vincent Hospital at Worcester Medical Center, Worcester, Massachusetts 01608, USA. rommelperillolu@yahoo.com
    • J Clin Apher. 2006 Dec 1;21(4):260-5.

    AbstractAcute disseminated encephalomyelitis (ADEM) is a demyelinating disease of the central nervous system that is associated with significant morbidity and mortality. Early recognition of the disease is of paramount importance; however, treatment options are limited because only case reports and small series are available in the literature. We report a case of a 42 year-old previously healthy man, whom we treated successfully with a combination regimen of methylprednisolone, IV immunoglobulin, and plasmapheresis early in the course of the disease.

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