• Rev Assoc Med Bras (1992) · Jan 2023

    Cryopreservation as a strategy for prevention of ovarian hyperstimulation syndrome in a public assisted reproduction service in São Paulo - Brazil.

    • Luma Caroline Gomes Mattos de Macedo, Mario Cavagna Neto, Artur Dzik, Andressa do Rosário Rocha, and Sônia Maria Rolim Rosa Lima.
    • Faculdade de Ciências Médicas da Santa Casa de São Paulo, Departamento de Obstetrícia e Ginecologia - São Paulo (SP), Brazil.
    • Rev Assoc Med Bras (1992). 2023 Jan 1; 69 (1): 164168164-168.

    ObjectiveThis study aimed to evaluate the prevalence of ovarian hyperstimulation syndrome (OHSS) and associated risk factors in patients undergoing fertilization cycles at risk of OHSS (≥15 antral follicles or ≥15 oocytes aspirated) and submitted to cryopreservation of all embryos in the Human Reproduction Service of the Pérola Byington Hospital (Referral Center for Women's Health) in São Paulo, SP, Brazil.MethodsThis cross-sectional, institutional, descriptive study of secondary data from patients' charts enrolled in the Assisted Reproduction Service of the Pérola Byington Hospital at risk of OHSS after controlled ovarian stimulation and submitted to cryopreservation of all embryos was conducted between January 2015 and September 2017.ResultsOHSS occurred in 47.5% of cycles, all with mild severity, and there were no moderate or severe cases of OHSS.ConclusionThe cryopreservation of all embryos is associated with a reduction in moderate and severe forms of OHSS. Risk factors for OHSS should be evaluated prior to initiation of treatment, with less intense stimulation protocols accordingly.

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