• Medicina clinica · May 2023

    Multicenter Study

    Triponderal mass index and markers of metabolic risk in children and adolescents with obesity.

    • Enrique Palomo Atance, Francisco Javier Caballero Mora, David Espadas Maciá, Mercedes Marbán Calzón, Pilar Sevilla Ramos, Lourdes García Villaescusa, María Jesús Dabad Moreno, José Ramón Muñoz-Rodríguez, and Rafael Ruiz Cano.
    • Endocrinología Pediátrica, Servicio de Pediatría, Hospital General Universitario de Ciudad Real, Grupo de Endocrinología Pediátrica de Castilla-La Mancha (GEPCAM), Ciudad Real, España. Electronic address: palomo.enrique@gmail.com.
    • Med Clin (Barc). 2023 May 12; 160 (9): 379384379-384.

    Background And ObjectiveTriponderal mass index (TMI) would estimate excess adiposity better than body mass index (BMI), maintaining stable values during childhood. This work aims to determine the correlation between TMI and markers of metabolic risk as well as set values of TMI that are related to an increase of metabolic risk.Material And MethodsMulticenter, observational, cross-sectional and prospective study in children under 14 years of age with obesity.Variablesage, sex, pubertal stage, weight, height, abdominal circumference, BMI, TMI, basal glucose and insulin, HOMA index, blood pressure, lipoprotein profile, transaminases and uric acid. BMI and TMI were expressed according to the values of the Barcelona longitudinal study. Statistical analysis was performed with the SPSS* program.ResultsOne hundred and ninety-nine patients (50.3% male), age 11.08 (2.48) years, TMI 19.68 (2.36)kg/m3. Correlation between TMI and abdominal circumference (r=0.571; p=0), insulin (r=0.198; p=0.005), HOMA index (r=0.189; p=0.008) and HDL-c (r=-0.188; p=0.008) was observed. IMT>20.15kg/m3 was associated with insulin≥15mIU/ml (p=0.029) and IMT>20.36kg/m3 with HDL-c<40mg/dl (p=0.023).ConclusionsTMI was correlated with increase of abdominal circumference, insulin and HOMA index and decrease of HDL-c. IMT>20kg/m3 can be associated with increased insulin and decreased HDL-c. Therefore, the IMT seems to be a useful parameter in the assessment of pediatric patients with obesity.Copyright © 2022 Elsevier España, S.L.U. All rights reserved.

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