• Michele Rizzi, Nicolò Castelli, Roberta Di Giacomo, Vittoria Cojazzi, Niccolò Innocenti, Vincenzo Levi, Vittoria Nazzi, and Marco Schiariti.
• Functional Neurosurgery Unit, Neurosurgery Department, Foundation IRCCS Carlo Besta Neurological Institute, Milan, Italy.
• World Neurosurg. 2023 Mar 1; 171: 136136.

AbstractThe supracerebellar transtentorial approach for the resection of brain lesion at the level of the mesial temporooccipital region is underused in the field of epilepsy surgery, despite the theoretical advantage of sparing normal brain structures, in particular in the dominant hemisphere for language. Hereby we present the case of a patient with a low-grade epilepsy associated tumor, presenting with weekly drug-resistant focal seizures, treated by a supracerebellar transtentorial lesionectomy. Surgery was uneventful and the histopathology revealed a pleomorphic low-grade neuroepithelial tumor of the young patient. At the 6-month follow-up, the patient did not present neurologic deficits and she never presented with seizures after surgery, so antiepileptic drug tapering started. The integration of supracerebellar transtentorial approach in the "armory" of the epilepsy neurosurgeon requires a dedicated expertise and an anesthesiologic setting used to manage the semisitting position; on the other hand, it could provide a relevant option to provide safe and complete lesionectomy in the mesial temporooccipital region, together with the more classical sublobar and transcerebral approaches (Video 1).Copyright © 2023 Elsevier Inc. All rights reserved.

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