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- Hannah Bromberg, Ann Guastella, Meghan Haas, Reem Akel, and David Craig.
- Department of Supportive Care, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, USA.
- J Palliat Med. 2023 Jul 1; 26 (7): 102410261024-1026.
AbstractTrigeminal neuralgia (TN) secondary to malignancy leads to significant distress and subsequently impacts a patient's quality of life. Use of methadone as a first-line opioid analgesic in this subset of oncology patients is uncommon and is rarely initiated after traditional first-line therapies have failed. We report two patients with TN secondary to tumor burden who experienced significant analgesia within 24 hours of methadone initiation.
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