• Gac Med Mex · Jan 2022

    Components of frailty, sarcopenia and their association with vitamin D deficiency. Cross-sectional, analytical study.

    • Karla B Carrazco-Peña, Katia Farías-Moreno, Mario Del Toro-Equihua, Zahira C Aguilar-Mancilla, Mariana Trujillo-Magallón, Miguel A Solórzano-Rodríguez, and Benjamín Trujillo-Hernández.
    • Faculty of Medicine, Universidad de Colima, Colima.
    • Gac Med Mex. 2022 Jan 1; 158 (6): 343348343-348.

    IntroductionIn older adults, the association of frailty and sarcopenia with vitamin D deficiency is well known, but the association of the components of frailty syndrome has been poorly studied.ObjectiveTo determine the association of the components of frailty and sarcopenia with vitamin D insufficiency in older adults.MethodsAdults were studied, in whom age, education, marital status, history of fractures, hospitalizations, anthropometric indicators, sarcopenia, Charlson index, polypharmacy, Fried's frailty phenotype, and plasma vitamin D were recorded; figures < 30 ng/mL were considered indicative of vitamin D insufficiency. Descriptive and inferential statistics were used for statistical analysis. The association was determined by binary logistic regression.ResultsOne-hundred and seventy-five adults with a mean age of 71.7 ± 6.7 years (95% CI = 60-90 years) were studied. Binary logistic regression showed that the variables associated with vitamin D deficiency were exhaustion (OR = 2.6, 95% CI = 1.0-6.5, p = 0.03), frailty (OR = 9.2, 95% CI = 2.5-34.1, p = 0.001) and pre-frailty (OR = 4.6, 95% CI = 2.1-10.0, p < 0.001).ConclusionThe frail and pre-frail phenotypes, as well as exhaustion, are associated with vitamin D insufficiency.Copyright: © 2022 Permanyer.

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