• Internal medicine · Sep 2023

    Case Reports

    Paralytic Ileus During Treatment of Pulmonary and Renal Tuberculosis in a Non-Human Immunodeficiency Virus Patient: An Unusual Presentation of Tuberculosis-immune Reconstitution Inflammatory Syndrome.

    • Toyohiro Hashiba, Mai Sugahara, Yui Ota, Ken Kaseda, Yusuke Kashiwagi, Motonobu Nakamura, Takayuki Shinohara, Mahoko Ikeda, Shu Okugawa, Kazuma Sugimoto, Kenichi Sasaki, Yoshifumi Hamasaki, Daisuke Yamada, Haruki Kume, Kyoji Moriya, and Masaomi Nangaku.
    • Division of Nephrology and Endocrinology, the University of Tokyo Hospital, Japan.
    • Intern. Med. 2023 Sep 1; 62 (17): 255925642559-2564.

    AbstractParalytic ileus as tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is extremely rare. We herein report a 44-year-old man with pulmonary and renal tuberculosis who developed paralytic ileus 14 days after starting antituberculosis therapy (ATT) despite an initial favorable response to ATT. Paralytic ileus was successfully managed with conservative care. He initially required hemodialysis because of obstructive uropathy due to renal tuberculosis, but he was able to withdraw from dialysis after placement of ureteral stents. TB-IRIS can affect organs other than the original sites of tuberculosis, and the combined use of steroids may be effective for its prevention and treatment.

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