• Internal medicine · Sep 2023

    Case Reports

    Successful Treatment with Definitive Concurrent Chemoradiotherapy Followed by Durvalumab Maintenance Therapy in a Patient with Tracheal Adenoid Cystic Carcinoma: A Case Report.

    • Erika Mikami, Shinji Nakamichi, Atsuhiro Nagano, Kazuhito Misawa, Anna Hayashi, Takehiro Tozuka, Natsuki Takano, Rintaro Noro, Katsuya Maebayashi, Hirotoshi Kubokura, Yasuhiro Terasaki, Kaoru Kubota, and Masahiro Seike.
    • Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Japan.
    • Intern. Med. 2023 Sep 15; 62 (18): 273127352731-2735.

    AbstractAdenoid cystic carcinoma (ACC) is a rare type of malignant tracheal tumor originating from the secretory glands. Complete surgical resection is the current standard of care for tracheal ACC. However, there have been few case reports of chemoradiotherapy for unresectable tracheal ACC. We herein report a 28-year-old man with unresectable tracheal ACC who received concurrent chemoradiotherapy (CCRT) followed by maintenance therapy with durvalumab. CCRT was completed with a good response and safety, and the patient is currently receiving durvalumab as maintenance therapy. Durvalumab after CCRT can be a treatment option for patients with unresectable tracheal ACC.

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