• Yitong Liu, Chan Li, Haiyan Sun, Fuli Kang, Zhenhong Zhang, and Chen Yue.
• Department of Gynecology and Obstetrics, The Second Hospital of Dalian Medical University, Dalian, Liaoning, China.
• Medicine (Baltimore). 2023 Jan 27; 102 (4): e32742e32742.

RationaleChoriocarcinoma is a highly invasive gestational trophoblastic neoplasm, usually metastasis to lung and brain, but occurrence of choriocarcinoma following spontaneous abortion presenting as a vertebral tumor is extremely rare, to the best of our knowledge. Because of the poor diagnosis and high malignancy, the low progression-free survival follows up.Patient ConcernsWe here are reporting a case of choriocarcinoma that presented with vertebral tumor induced paralysis of limbs and incontinence of urine.DiagnosisCombined with the childbearing history, high β-human chorionic gonadotrophinin levels, and imaging examination, a clinical diagnosis was made exactly. Till the pathological results after the operation of lumbar spinal canal tumorectomy, the diagnosis was exactly clear.InterventionsAfter performing the laminectomy, the fierce bleeding follows up, just did the temporary limited decompression. Because of the vertebral artery embolization, lumbar spinal canal tumorectomy, spinal canal and root canal decompression, subdural decompression and hematoma removal were performed.OutcomesAfter performing the operation and chemotherapy timely and positively, the patient lost consciousness and died due to the pulmonary embolism at last.LessonsThis is the first case report describing choriocarcinoma with metastases to the spine amongst Chinese population as well. Early metastasis is one of the marked tendencies of choriocarcinoma, but spine metastasis and the related spinal oppressional symptoms were found instead of vaginal bleeding in this case, which is indeed rare.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

29 keywords...

hide…