• Brit J Hosp Med · Jan 2023

    Review

    Achalasia: investigation and management.

    • Naim Slim and James Ml Williamson.
    • Department of General Surgery, The Great Western Hospital, Swindon, UK.
    • Brit J Hosp Med. 2023 Jan 2; 84 (1): 191-9.

    AbstractAchalasia, characterised by the absence of peristalsis and failure of relaxation of the lower oesophageal sphincter, is an uncommon degenerative condition that results in dysphagia. If left untreated it can lead to aspiration, oesophageal perforation, oesophagitis and malnutrition. It has a range of immune, allergic, viral and genetic aetiological causes. Successful diagnosis relies on the use of oesophagogastroduodenoscopy, barium swallow and oesophageal manometry to characterise the severity of the disease and to rule out underlying malignancy. Although no treatment can reverse the degenerative process, therapeutic strategies including lifestyle modification, medication, endoscopic and operative intervention can help to reduce symptoms. This article reviews the latest methods used to investigate and manage achalasia.

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