• Marcus Nemeth, Marielle Ernst, Thomas Asendorf, Simon Wilmers, Carlo Pancaro, Nils Kunze-Szikszay, and Clemens Miller.
• Department of Anaesthesiology, University Medical Centre Goettingen, Robert-Koch-Straße 40, 37075 Goettingen, Germany. Electronic address: marcus.nemeth@med.uni-goettingen.de.
• Resuscitation. 2023 Mar 1; 184: 109702109702.

ObjectiveTo validate the ERC-recommended facial landmark-distance for oropharyngeal airway sizing in children.MethodsWe conducted a prospective observational study in anaesthetised, spontaneously breathing children ≤12 years undergoing cranial MRI. Oropharyngeal airways were inserted following the distance from the maxillary incisors to the mandibular angle. Primary outcome was the rate of properly sized oropharyngeal airways on MRI, defined as the distal end positioned within 10 mm from the epiglottis without contacting it. Secondary outcomes were the occurrence of tongue protrusion, oropharyngeal airways clinical efficacy, and related adverse events. Furthermore, we calculated probabilities for the estimation of proper size when considering five facial landmark-distances and optimal rules based on biometric parameters.ResultsIn 94 children with a mean (SD) age of 4.7 (±3) years, 47.9% [95%-CI 38%-57.9%] oropharyngeal airways were properly sized, while 23.4% [95%-CI 15.9%-33%] were undersized, and 28.7% [95%-CI 20.5%-38.7%] oversized. Tongue protrusion occurred in 59.1% [95%-CI 38.2%-77.2%] of undersized and 15.6% [95%-CI 7.6%-29.2%] of properly sized oropharyngeal airways. No oropharyngeal airway required replacement. Comparing probabilities for five landmark-distances, "maxillary incisors to the angle of the mandible" proved superior for proper sizing at 41.2% [95%-CI 32%-51.7%]. The best-fit formula was "22.43 + 17.54 × log(weight[kg])" with a probability of 61.7% [95%-CI 51.5%-70.9%].ConclusionAlthough the facial landmark-distance "maxillary incisors to the angle of the mandible" does not reliably predict oropharyngeal airway size, no clinical problems have been encountered. Since it can be considered the least inaccurate facial landmark-distance, it can serve as an approximation, but the efficacy of oropharyngeal airways should be evaluated clinically.Registered Clinical TrialGerman Clinical Trials Register; DRKS00025918.Copyright © 2023 Elsevier B.V. All rights reserved.

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