• Amanda Almeida Leite, Augusto César Leal da Silva Leonel, CastroJurema Freire Lisboa deJFL0000-0001-8346-2259PhD. Professor, Oral Pathology Unit, School of Dentistry, Universidade Federal de Pernambuco (UFPE), Recife (PE), Brazil., Elaine Judite de Amorim Carvalho, Pablo Agustin Vargas, Luiz Paulo Kowalski, and PerezDanyel Elias da CruzDEDC0000-0002-4591-4645PhD. Professor, Oral Pathology Unit, School of Dentistry, Universidade Federal de Pernambuco (UFPE), Recife (PE), Brazil..
• MSc. Student, Oral Pathology Unit, Piracicaba Dental School, Universidade Estadual de Campinas (UNICAMP), Piracicaba (SP), Brazil.
• Sao Paulo Med J. 2018 Mar 1; 136 (2): 165169165-169.

BackgroundOnly a few studies have evaluated the clinicopathological features of oral squamous cell carcinoma (SCC) in Brazil, and most were conducted in the most industrialized region of the country, i.e. the southeastern region. The aim of this study was to evaluate the clinicopathological features of this malignant neoplasm in northeastern Brazil.Design And SettingRetrospective study performed in an oral pathology laboratory in Recife, Brazil.MethodsAll cases of oral SCC that occurred between 2000 and 2015 were studied. Clinical data were recorded and histological slides were reviewed. Statistical analysis was performed using the chi-square test (P ≤ 0.05).ResultsA total of 194 cases were evaluated. The male-to-female ratio was 1.5:1. The mean age was 65.4 years, and only 6.6% of the cases occurred in patients younger than 41 years. Most tumors consisted of well-differentiated SCC (54.6%).ConclusionsThe findings of this study highlight the higher prevalence of oral SCC among women and the increasing number of cases among young patients. Thus there is no specific risk group for oral SCC, as in the past. This fact needs to be taken into consideration in clinical routine care, so that apparently innocuous malignant lesions do not go unnoticed in these individuals.

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