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- Ravindra Alok Gupta, Howard Lee, and Obianuju Okocha.
- From the Department of Anesthesiology, Northwestern University, Chicago, Illinois.
- A A Pract. 2023 Feb 1; 17 (2): e01659e01659.
AbstractPenicillin allergy is the most reported immunoglobulin E (IgE)-mediated reaction. About 10% of the general population and 20% of hospitalized patients have a history of penicillin allergy. Unconfirmed penicillin allergy with subsequent administration of second-line antibiotics has been associated with increased morbidity. However, when penicillin allergy testing is performed, the incidence of IgE-mediated reactions is extremely low; in fact, the negative predictive value of penicillin allergy testing exceeds 99%. This article aims to briefly describe implementing safe penicillin allergy testing as a routine test during the preoperative evaluation of surgical patients.Copyright © 2023 International Anesthesia Research Society.
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