• Xue Zhao, Jie Xu, Ming-Yue Wang, Zi-Wei Hou, Hui-Shan Shi, and Xiao-Xia Zhang.
• Institute of Chinese Medicine Literature, and Culture, Shandong University of Traditional Chinese Medicine, Jinan, China.
• Medicine (Baltimore). 2023 Feb 3; 102 (5): e32804e32804.

BackgroundThis study aimed to observe the clinical effects of Xiao-xian decoction combined with acupoint application therapy (AAT) for treating pediatric adenoid hypertrophy (AH).MethodsWe randomly divided 93 AH children into 3 groups: AAT alone; Xiao-xian decoction + AAT; control: Montelukast oral therapy. All participants were treated for a month. We used the traditional Chinese medicine syndrome score to evaluate the clinical efficacy and the obstructive sleep apnea-18 scale to evaluate the quality of life.ResultsThe major symptoms (nasal congestion, open mouth breathing, snoring, and tongue image) and secondary symptoms of patients treated with Xiao-xian decoction + AAT significantly improved compared to before treatment. The pairwise comparison between groups showed that snoring, tongue, secondary symptoms, and total effective rate of the combined treatment group were better than the control and AAT alone. Additionally, the open-mouth breathing, quality of life, and recurrence rate did not differ after treatment.ConclusionOral Xiao-xian decoction combined with AAT significantly improved the symptoms and signs of nasal congestion, open-mouth breathing, snoring, tongue, and quality of life of AH children and may be used as a long-term treatment for AH.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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