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Comment Randomized Controlled Trial
In hypertension, evening vs. morning dosing of antihypertensive drugs did not differ for major CV outcomes at 5.2 y.
- KoKo Aung and Thwe Htay.
- Paul L. Foster School of Medicine, El Paso, Texas, USA (K.A., T.H.).
- Ann. Intern. Med. 2023 Feb 1; 176 (2): JC16JC16.
AbstractMackenzie IS, Rogers A, Poulter NR, et al. Cardiovascular outcomes in adults with hypertension with evening versus morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet. 2022;400:1417-25. 36240838.
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