• Enora Atchade, Adrien Arsène, Sylvain Jean-Baptiste, Tran DinhAlexyAAPHP, CHU Bichat-Claude Bernard, DMU PARABOL, 46 rue Henri Huchard, 75018 Paris, France; INSERM U1148, LVTS, CHU Bichat-Claude Bernard, 46 rue Henri Huchard, 75018 Paris, France; Université de Paris, UFR Diderot, France., Sébastien Tanaka, Jules Stern, Brice Lortat-Jacob, Sacha Rosencwajg, Tiphaine Goletto, Hervé Mal, Iannis Ben Adballah, Yves Castier, Christian de Tymowski, and Philippe Montravers.
• APHP, CHU Bichat-Claude Bernard, DMU PARABOL, 46 rue Henri Huchard, 75018 Paris, France. Electronic address: enora.atchade@aphp.fr.
• Resuscitation. 2023 Mar 1; 184: 109720109720.

BackgroundThe outcomes of lung transplantation (LT) recipients who received a graft from a brain-dead donor after successful resuscitation from cardiac arrest (CA donors) have been poorly described. This study compared the one-year survival of LT recipients depending on the CA status of the donor.MethodsThis prospective observational single-centre study analysed all consecutive patients who underwent LT at Bichat Claude Bernard Hospital, Paris, between January 2016 and December 2020. All donors who experienced CA prior to organ donation, regardless of rhythm or duration, were considered CA donors. The postoperative complications and outcomes of LT recipients were analysed. The one-year survival was compared using Kaplan-Meier curves and log-rank tests. Independent risk factors for one-year mortality were assessed using multivariate analysis (p < 0.05 was considered significant). The Paris North Hospitals Institutional Review Board approved the study.ResultsA total of 236 LT recipients were analysed and 66 (28%) received a graft from a CA donor. The median durations of no/low flow were 4 [0-10]/20 [15-30] minutes, respectively. Shockable and non-shockable rhythms were observed in 11 (17%) and 47 (72%) of the CA donors, respectively. The characteristics of the grafts and early postoperative complications were not different in the CA and non-CA groups. Receiving a graft from a CA donor was not an independent risk factor for recipient one-year mortality.ConclusionReceiving a graft from a CA donor did not worsen the outcome of LT recipients. Acceptation of these grafts must be systematically considered to increase the pool of available grafts.Copyright © 2023 Elsevier B.V. All rights reserved.

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