• Alessandro Casiraghi, Claudio Galante, Mohamed Rohayem, Giulio Vittone, Marco Domenicucci, Stefano Cattaneo, Marco Paderno, Giuseppe Grava, Evelyn Van Hauwermeiren, and Giuseppe Milano.
• Department of Bone and Joint Surgery, ASST Spedali Civili, Brescia, Italy.
• Injury. 2023 Apr 1; 54 (4): 108210871082-1087.

BackgroundThe development of a pelvic wound infection in the presence of hardware after open reduction and internal fixation presents a clinical dilemma and there is little literature to aid in decision-making. The purpose of this study was to describe the possibility of debridement, antibiotic pearls and retention of the implant (DAPRI) procedure to eradicate the infection.MethodsTumor-like debridement, antibiotic pearls and retention of the implant (DAPRI) aimed to remove the biofilm allowing a higher and prolonged local antibiotic concentration by using calcium sulfate antibiotic-added beads. Wound status, radiological signs of bone healing, gait and functional activity of the patient were evaluated.ResultsSeven patients underwent this technique. The mean follow up time was nine months (range: 6 -16 months). Complete wound healing was achieved in all the patients with no major complications. Average time of bony union was 4.3 months (range: 3-6 months) with no need for implant removal.ConclusionThe DAPRI technique might represent a safe and more conservative treatment for management of early fracture-related infections (FRI) of the pelvis and acetabulum.Copyright © 2023 Elsevier Ltd. All rights reserved.

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