• Chest · Feb 2023

    Case Reports

    A Woman With Progressive Dyspnea and Seronegative Rheumatoid Arthritis.

    • Madeline Smoot, Johnny F Jaber, Biplab K Saha, and Adam Austin.
    • Department of Medicine, University of Florida, Gainsville, FL.
    • Chest. 2023 Feb 1; 163 (2): e63e67e63-e67.

    AbstractA 66-year-old woman with a medical history of seronegative rheumatoid arthritis on long-standing methotrexate and adalimumab therapy was referred to the pulmonary clinic for abnormal chest imaging. The patient was also under evaluation by rheumatology physicians for increased fatigue, nonproductive cough, and recurrent sinus infections. At the time of the initial pulmonary visit, the patient complained of acute onset of bilateral blurry vision and subsequently was diagnosed with anterior uveitis and received ophthalmic steroids with significant improvement. The patient's biologic therapy was discontinued because of a concern for possible drug toxicity. Over the course of 4 months, the patient experienced worsening dyspnea with exertion. She was a lifelong nonsmoker and had no history of recent travel. However, on review of possible environmental exposures, patient stated using feather pillows and bedding for several decades.Copyright © 2022 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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