• Minerva anestesiologica · Apr 2023

    Review

    Potential nutritional and pharmacological treatment of glycocalyx alterations during sepsis.

    • Carola Pergolizzi, Federico Franchi, Fabio S Taccone, Jean-Charles Preiser, and Sabino Scolletta.
    • Anesthesia and Intensive Care Unit, University Hospital of Siena, University of Siena, Siena, Italy.
    • Minerva Anestesiol. 2023 Apr 1; 89 (4): 341350341-350.

    AbstractDuring sepsis, a combination of pathophysiological insults disrupts the glycocalyx. The thickness of the glycocalyx is correlated with parameters of disease severity, making it a potential new and independent target for therapeutic strategies in sepsis. The aim of this review was to examine potential beneficial effects of nutritional and pharmacological measures on glycocalyx alterations during sepsis and their timing.

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