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- Tomoya Tateishi, Sho Shimada, Takashi Yamana, Yuki Iijima, Rie Sakakibara, Takahiro Mitsumura, Sho Shibata, Takayuki Honda, Tsuyoshi Shirai, Tsukasa Okamoto, Meiyo Tamaoka, Tsuneo Sasai, and Yasunari Miyazaki.
- Department of Respiratory Medicine, Tokyo Medical and Dental University, Japan.
- Intern. Med. 2023 May 1; 62 (9): 132313281323-1328.
AbstractCoronavirus disease 2019 (COVID-19) pneumonia is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is frequently accompanied by various sequelae. Interstitial lung diseases (ILDs) are observed in COVID-19 pneumonia patients after recovery, probably due to persistent inflammation in the lungs. We herein report a case of ILD with anti-signal recognition particle antibodies following severe COVID-19 pneumonia. The patient was diagnosed with ILD three months after COVID-19 pneumonia. Although the exact mechanism is unknown, the autoantibody-induced immune response might have been the pulmonary fibrosis trigger in this patient.
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