• Internal medicine · Sep 2023

    Case Reports

    Advanced Appendiceal Cancer with Systematic Metastasis without Gastrointestinal Symptoms Found by Subcutaneous Tumor.

    • Satoshi Nakamura, Yorinari Ochiai, Yuki Nishihara, Anri Koyanagi, Yasurou Miura, Daisuke Kikuchi, Yutaka Takazawa, Hiroya Kuroyanagi, and Shu Hoteya.
    • Department of Gastroenterology, Toranomon Hospital, Japan.
    • Intern. Med. 2023 Sep 15; 62 (18): 265526602655-2660.

    AbstractAn 86-year-old woman with a subcutaneous nodule in her left axilla visited our hospital. She had no gastrointestinal symptoms, but contrast-enhanced computed tomography revealed a cecal mass and systemic metastasis, including cutaneous, bone, peritoneal dissemination and ascites. Colonoscopy revealed a circumferential, elevated cecal lesion. She underwent right hemicolectomy to prevent colon obstruction. The pathological diagnosis was poorly differentiated adenocarcinoma (por1>tub2>muc) arising from the appendix with a BRAFV600E mutation and microsatellite instability-high. Chemotherapy was administered, and she is currently still alive and undergoing chemotherapy. We describe a rare case of advanced appendiceal cancer without gastrointestinal symptoms diagnosed due to cutaneous metastasis.

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