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- Yesica Lamberto, Cecilia Domínguez, Alicia Arechavala, Pablo Saúl, Viviana Chediack, and Eleonora Cunto.
- Hospital Francisco Javier Muñiz, Buenos Aires, Argentina.
- Medicina (B Aires). 2023 Jan 1; 83 (1): 829582-95.
AbstractInvasive aspergillosis (IA) is a serious disease with high mortality. There are several risk factors and in-hospital outbreaks related with construction have been described. An entity related to COVID-19 infection, known as COVID-19 associated pulmonary aspergillosis (CAPA), has recently appeared. Early and appropriate treatment is of paramount importance, especially in immunocompromised and critically ill patients. Diagnosis is based on recognition of predisposing factors, clinical signs, imaging, direct examination, culture, histopathology, and biomarkers such as galactomannan. The drug of choice is voriconazole, but alternative therapies must be taken into account given the increasing presence of resistant isolates.
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