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- Zahir Kanjee, Katherine Berg, Taison D Bell, and Eileen E Reynolds.
- Division of General Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts (Z.K., E.E.R.).
- Ann. Intern. Med. 2023 Feb 1; 176 (2): 253259253-259.
AbstractSepsis is a potentially life-threatening systemic dysregulatory response to infection, and septic shock occurs when sepsis leads to systemic vasodilation and subsequent tissue hypoperfusion. The Surviving Sepsis Campaign published updated guidelines in 2021 on the management of sepsis and septic shock. Here, in the context of a patient with septic shock, 2 critical care specialists discuss and debate conditional guideline recommendations on using lactate to guide resuscitation, the use of balanced crystalloids versus normal saline, and the use of corticosteroids.
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