• Ir J Med Sci · Oct 2023

    Pregnancy outcomes following recurrent miscarriage.

    • Niamh Fee, Aoife McEvoy, Sarah Cullen, Sam Doyle, David Crosby, and Cathy Allen.
    • National Maternity Hospital, Dublin, Ireland. drniamhfee@gmail.com.
    • Ir J Med Sci. 2023 Oct 1; 192 (5): 225522582255-2258.

    BackgroundRecurrent miscarriage affects 1-2% of the population, and the literature has focussed on causes, treatment, and live birth rate.AimThis study aimed to assess the reproductive outcomes for patients who attended a specialist recurrent miscarriage clinic for investigation and treatment.MethodsProspective analysis of all patients who attended a recurrent miscarriage clinic from January 2014 to January 2021.ResultsOf the 488 patients who attended a specialist clinic, 318 had a further pregnancy with 299 included in this study. The median age was 37 years, with 55.6% having a previous live birth. The subsequent live birth rate was 75.3%, 22.0% had a further pregnancy loss, 1.7% had an ongoing pregnancy, and 1% attended another institution after the second trimester. The rate of preeclampsia was 2.2%, pregnancy-induced hypertension was 2.2%, fetal growth restriction was 5.3%, preterm birth ≤ 34 weeks was 1.8%, and preterm birth > 34 weeks < 37 weeks was 6.6%.ConclusionPatients who attend a dedicated recurrent miscarriage clinic for investigation and treatment have a high live birth rate in a subsequent pregnancy. A subsequent pregnancy following recurrent pregnancy loss does not appear to be associated with an increased risk of adverse pregnancy outcomes.© 2023. The Author(s), under exclusive licence to Royal Academy of Medicine in Ireland.

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