• Ali Ümit Yener, Adnan Yalçinkaya, Özlem Yener, Ekin Can Çelik, Onur Hanedan, Mustafa Cüneyt Çiçek, and Ömer Faruk Çiçek.
• Department of Cardiovascular Surgery, University of Health Science Antalya Education and Training Hospital, Antalya, Turkey.
• Medicine (Baltimore). 2023 Feb 17; 102 (7): e33008e33008.

AbstractThis study aimed to investigate the effects of pharmacomechanical thrombectomy on novel complete blood count parameters in deep venous thrombosis. This retrospective study included 242 patients aged >18 years who were treated for deep venous thrombosis. Patients were grouped as follows: group 1 was accepted as having interventional operations (n = 123) and group 2 was accepted as having only medical advice (n = 119). Routine complete blood count parameters, the neutrophil-to-lymphocyte ratio (NLR), and the platelet-to-lymphocyte ratio (PLR) were compared. There was no difference between the groups in terms of admission hemoglobin, hematocrit, mean platelet volume, NLR and PLR (P = .11, P = .24, P = .55, P = .93, and P = .96, respectively). In the pharmacomechanic thrombectomy group, NLR and PLR were significantly reduced after intervention when compared to the admission values (P < .001 and P < .001, respectively). However, the NLR and PLR values of medically treated patients did not differ significantly from their baseline values (P = .16 and P = .08, respectively). In this study, we effectively removed the thrombus load in blocked proximal veins using pharmacomechanical thrombectomy and observed a significant decrease in NLR and PLR, which are current, inexpensive, and accessible parameters.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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