• Joo Yeon Park and Jae Hee Chung.
• Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
• Medicine (Baltimore). 2023 Feb 17; 102 (7): e33016e33016.

RationaleAn omphalocele is an abdominal wall birth defect, and a giant omphalocele (GO) is defined as an omphalocele having a diameter >5 cm or containing a herniated liver. GOs are usually treated in stages and in this case, during the silo reduction, dehiscence occurred at the suture site of the axis ring and skin edge, which was repaired using synthetic absorbable mesh.Patient ConcernsA girl infant was born at 36 weeks with a GO of 8 cm diameter, and herniated multiple organs such as the small bowel, cecum, appendix, and the entire liver. Even after the staged repair technique for the GO silo, wound dehiscence between the ring of the silo and the edge of the skin occurred and gradual reduction failed.DiagnosisA GO of 8 cm diameter, which was found during prenatal ultrasonography.InterventionsRevision was performed to repair the defect. The small bowel and liver were still prolapsed, and there were severe adhesions. After adhesiolysis, the muscle layer of the abdominal wall was repaired using the tissue matrix, but the skin could not be repaired. After the second operation, the defect wound was dressed as sterilely as possible.OutcomesThe abdominal wall defect was repaired completely; there were no residual complications.LessonsRepair of GOs using an acellular porcine dermal matrix can be considered a viable treatment option.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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