• Medicine · Feb 2023

    Impact of age for overall survival in head and neck sarcoma.

    • Hidenori Suzuki, Gaku Takano, Satoshi Tsukushi, Masashi Ando, Yasushi Yatabe, Takeshi Kodaira, Daisuke Nishikawa, Shintaro Beppu, Yasuhisa Hasegawa, and Nobuhiro Hanai.
    • Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
    • Medicine (Baltimore). 2023 Feb 17; 102 (7): e32966e32966.

    AbstractThe purpose to the present study is to research the association between age at surgery and survival outcomes of patients with sarcoma in head and neck. Twenty-six patients with head and neck sarcoma who underwent by surgery from 2003 to 2017 were enrolled in the present observation study. Patients who did not undergo chemotherapy were significantly older age at surgery by Mann-Whitney U test. Fifty-five was the cutoff age that predicted death by receiver operating curve analysis. Shorter survival rates of overall, disease-specific, local recurrence-free and disease-free were associated with older age by log-rank test. Age (≥55 years/<55 years) was correlated with shorter overall survival by multivariate analysis of Cox's proportional hazards model adjusting with chemotherapy (absence/presence). In conclusion, older age predicts worse overall survival in head and neck sarcoma.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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