• Internal medicine · Feb 2023

    A Woman with Rheumatoid Arthritis Who Successfully Delivered a Healthy Child with Continuous Administration of Sarilumab Throughout Pregnancy.

    • Satoshi Mizutani, Yuki Okunishi, Tatsuya Tamada, Hiroyuki Tanaka, Yuhei Ito, Yoshiki Yamamoto, Asa Kitamura, Hiroaki Tanaka, Tomoaki Ikeda, and Ayako Nakajima.
    • Center for Rheumatic Diseases, Mie University Hospital, Japan.
    • Intern. Med. 2023 Feb 15; 62 (4): 633636633-636.

    AbstractWe herein report a patient with rheumatoid arthritis (RA) who successfully delivered a healthy child with continuous administration of sarilumab throughout pregnancy. She delivered her first child, a healthy boy, following in vitro fertilization-embryo transfer (IVF-ET) while using etanercept and low-dose prednisolone. Disease activity persisted after delivery, so etanercept was switched to sarilumab. She became pregnant by IVF-ET again. Because RA was still active, sarilumab was continued during pregnancy. She delivered a healthy girl at the 38th week of gestation by Caesarean section. No abnormalities were detected at or within 6 months after birth. Sarilumab was safe and effective in this pregnant woman with RA.

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