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Case Reports
Neurofibromatosis Type 1 with a Giant Diffuse Plexiform Neurofibroma Invading the Liver: A Case Report.
- Yuko Yokogawa, Tomohiro Suzuki, Hiroyuki Suzuki, Rena Nemoto, Hiroshi Shimizu, Tsuyoshi Ueda, Daiki Uchihara, Yoshinori Okubo, Osamu Ichii, Mayumi Tai, Yutaka Ejiri, and Masaru Harada.
- Department of Gastroenterology, Fukushima Rosai Hospital, Japan.
- Intern. Med. 2023 Oct 15; 62 (20): 297129752971-2975.
AbstractPlexiform neurofibromas (PNs) occur in approximately 50% of patients with neurofibromatosis type 1 (NF1). PNs are rare in the abdominal cavity and especially rare in hepatobiliary lesions. A 31-year-old man with NF1 had a tumor extending along the celiac artery, superior mesenteric artery, and intrahepatic portal vein. We diagnosed him with diffuse PN based on liver tumor biopsy findings and the tumor form. Because the tumor had invaded along the intrahepatic portal vein, surgical resection was deemed difficult, and the patient was followed up with imaging studies. The patient remained asymptomatic without tumor growth.
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