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- Naokazu Sato, Koji Inagaki, Masahiro Takanashi, Reiko Muto, Noritoshi Kato, Shoichi Maruyama, and Toshiyuki Akahori.
- Department of Nephrology, Ebina General Hospital, Japan.
- Intern. Med. 2023 Oct 1; 62 (19): 286528702865-2870.
AbstractMyoglobin is a well-known cause of acute kidney injury (AKI) due to rhabdomyolysis. However, whether or not removing serum myoglobin by on-line hemodiafiltration (OHDF) improves the kidney function remains unclear. We herein report a patient with a history of methamphetamine abuse who developed AKI due to rhabdomyolysis. A urinalysis and blood collection results obtained before and after OHDF demonstrated that OHDF improved the kidney function by removing a large amount of serum myoglobin rather than via urinary excretion. In conclusion, OHDF may prevent AKI progression effectively when the urine volume is insufficient.
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