• Internal medicine · Jan 2023

    A J-shaped Relationship between Sleep Duration and the Risk of Insulin Resistance in a General Japanese Population.

    • Hisashi Adachi, Akiko Matsumura, Mika Enomoto, Ako Fukami, Nagisa Morikawa, Yume Nohara, Maki Yamamoto, Hiromi Sato, Tatsuyuki Kakuma, and Yoshihiro Fukumoto.
    • Department of Internal Medicine, Division of Cardiovascular Medicine, Kurume University School of Medicine, Japan.
    • Intern. Med. 2023 Jan 1; 62 (4): 511517511-517.

    AbstractObjective Data on the role of sleep in the risk of insulin resistance (IR) are lacking. We therefore examined the association between sleep duration and IR in a general Japanese population. Methods Data of 1,344 individuals 34 to 89 years old from the Tanushimaru Study were analysed. IR was calculated using the fasting plasma glucose level×fasting insulin level/405, i.e. the homeostasis model assessment of IR (HOMA-IR). IR was defined as a HOMA-IR ≥1.73 based on the diagnostic criteria used in Japan. Information regarding sleep duration was collected via questionnaire. Results The frequencies of IR and metabolic syndrome (MetS) were 36.7% and 26.9%, respectively. A J-shaped relationship between sleep duration and IR was observed, and the same relationship was also shown between sleep duration and MetS; however, the relationship with MetS disappeared after adjusting for age, sex, and other confounding factors. Conclusion A J-shaped relationship was observed between sleep duration and the risks of IR in a general Japanese population.

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