• Dusica M Stamenkovic, Jumah G Ahmad, Ruggero M Corso, Dragana Unic Stojanovic, Jeffrey P Radabaugh, Martin J Citardi, and Davide Cattano.
• Department of Anesthesiology and Intensive Care, Military Medical Academy, Belgrade, Serbia.
• Minerva Anestesiol. 2023 Apr 1; 89 (4): 316330316-330.

AbstractA sound anesthesiologist-surgeon collaboration is crucial for the success of functional endoscopic sinus surgery (FESS). The aim of this narrative review was to describe if and how anesthetic choice can decrease bleeding and improve visibility in the surgical field (VSF) and thus contribute to successful FESS. A literature search was conducted on evidence-based practices published from 2011 to 2021 describing perioperative care, intravenous/inhalation anesthetics, and operative approaches for FESS and their effects on blood loss and VSF. With regards to preoperative care and operative approaches, best clinical practices include topical vasoconstrictors at the time of surgery, medical management (steroids) preoperatively, and patient positioning, as well as anesthetic techniques including controlled hypotension, ventilation settings, and anesthetics choices. Four out of five meta-analyses and six out of 11 randomized controlled trials favored total intravenous anesthesia (TIVA) over inhalation anesthesia (IA) for improved VSF. The effects on VSF were more dependent on adjunct medications used (remifentanil, alpha-2 agonists, etc.), rather than the choice of anesthetic technique (i.e., TIVA vs. IA). The current literature is inconclusive regarding the impact of anesthetic choice on VSF during FESS. We recommend that anesthesiologists use the anesthetic technique with which they are most comfortable to facilitate efficiency, recovery, cost, and collaboration with the perioperative team. Future studies should be designed to consider disease severity, the method for measuring blood loss, and a standardized VSF score. Studies should also investigate the long-term effects of TIVA- and IA- induced hypotension.

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