• Hailong Hu, Yating Wu, Yaqin Zhang, Li Zhang, Jianfa Zhang, and Rui Zhang.
• Department of General Surgery, Huanghe Sanmenxia Hospital, Sanmenxia, China.
• Medicine (Baltimore). 2023 Feb 10; 102 (6): e32714e32714.

IntroductionCronkhite-Canada syndrome (CCS) is currently considered to be a non-hereditary disease, which is relatively rare clinically. It is also known as polyposis hyperpigmentation alopecia nail dystrophy syndrome, it is a syndrome characterized by gastrointestinal polyposis and ectodermal changes, the main manifestations are gastrointestinal symptoms, skin pigmentation, alopecia, and hypothyroidism.Case PresentationIn this paper, the clinical characteristics, diagnosis and treatment of a case of CCS admitted to Huanghe Sanmenxia Hospital were analyzed. In the course of treatment, traditional Chinese medicine was used, but no hormone, and the patient's clinical symptoms were greatly relieved.ConclusionsCCS is rare, there is no specific treatment, and traditional Chinese medicine may can greatly relieve the clinical symptoms of patients. However, it's still having to be verified by a large sample, multi-center, long-term treatment follow-up studies.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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