• Internal medicine · Oct 2023

    Review Case Reports

    Adult-onset Still's disease with Acute Kidney Injury Requiring Hemodialysis: A Case Report and Literature Review.

    • Kenji Saito, Jumpei Temmoku, Yuya Sumichika, Shuhei Yoshida, Eisuke Takano, Shuhei Watanabe, Haruki Matsumoto, Yuya Fujita, Naoki Matsuoka, Tomoyuki Asano, Shuzo Sato, Hiroshi Watanabe, and Kiyoshi Migita.
    • Department of Rheumatology, Fukushima Medical University School of Medicine, Japan.
    • Intern. Med. 2023 Oct 1; 62 (19): 290129062901-2906.

    AbstractAdult-onset Still's disease (AOSD) is characterized by high spiking fever, evanescent rash, and arthritis. However, AOSD rarely presents with severe acute kidney injury (AKI). We herein present the case of a 56-year-old woman with new-onset AOSD who rapidly developed AKI. A physical examination and laboratory data revealed spiking fever, evanescent rash, thrombocytopenia, hyperferritinemia, and azotemia. The patient was diagnosed with AOSD complicated by AKI and macrophage activation syndrome. Treatment with high-dose steroids, hemodialysis, and plasma exchange successfully resolved her AKI. In this report, we review previously published reports on AOSD accompanied by AKI and discuss this rare complication in AOSD.

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