• Joji Ueno, Renato De Mayrinck Salgado, Dani Ejzenberg, Filomena Marília Henriques Carvalho, Eduardo Carvalho de Arruda Veiga, José Maria Soares Júnior, and Edmund Chada Baracat.
• Universidade de São Paulo, Faculdade de Medicina, Disciplina de Ginecologia, Departamento de Obstetricia e Ginecologia - São Paulo (SP), Brazil.
• Rev Assoc Med Bras (1992). 2023 Jan 1; 69 (1): 727772-77.

ObjectiveThis study sought to evaluate the influence of time (early <90 days and late >90 days) and endometrial injury on pregnancy success.MethodsThis is a retrospective study in which all infertile women who underwent at least one in vitro fertilization cycle at Clinica Gera between 2010 and 2015 were considered for inclusion. We included patients with a normal ovarian reserve and regular menses at intervals of up to 30 days. A total of 315 patient files were reviewed, and the study group was composed of patients who faced fertility issues and had male-caused infertility or idiopathic infertility. Also, women with male or unknown cause of infertility who have performed endometrial biopsy and have undergone embryo transfer up to 180 days after this procedure between 2010 and 2015 were included. The patients were divided into two groups according to the interval between biopsy and embryo transfer: group 1 (early-an interval of <90 days) and group 2 (late-an interval of >90 days and up to 180 days).ResultsThe results were superior for the group with an interval of less than 90 days relative to the group with an interval of more than 90 days (p<0.04). The pregnancy rates for group 1 and group 2 were 58.5% and 43.4%, respectively. The odds ratio for pregnancy success was 1.63 (95% confidence interval: 1.04 to 2.55).ConclusionThe early transfer of embryos (<90 days) may produce better results with a high rate of pregnancy. Further studies are necessary to identify the mechanism involved in this phenomenon.

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