• J Postgrad Med · Apr 2023

    Case Reports

    Bullous hemorrhagic dermatosis: A rare cutaneous reaction of heparin.

    • N Dhattarwal and R Gurjar.
    • Department of Dermatology and STD, V.M.M.C. and Safdarjung Hospital, New Delhi, India.
    • J Postgrad Med. 2023 Apr 1; 69 (2): 979897-98.

    AbstractBullous hemorrhagic dermatosis is a rare cutaneous reaction of heparin, a commonly used anticoagulant. Exact etiopathogenesis remains elusive but immune related mechanisms as well as dose dependent relationship have been proposed. Clinically, it is characterized by asymptomatic, tense hemorrhagic bullae on extremities or abdomen occurring 5-21 days after initiation of therapy. We report bilateral symmetrically grouped lesions, in a previously unreported distribution of this entity in both the forearms in a 50-year-old male admitted with acute coronary syndrome on oral ecosprin, oral clopidogrel and subcutaneous enoxaparin. The condition is self-resolving and discontinuation of drug is not required.

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