• Xu Yao, Yi Jin, Chunlan Gao, Yuqin Zhang, Yun Lu, Xiaoting Li, and Lili Ma.
• Department of Cardiovascular Medicine of Kunshan Hospital of Traditional Chinese Medicine, Suzhou, Jiangsu Province, China.
• Medicine (Baltimore). 2023 Mar 3; 102 (9): e33183e33183.

BackgroundFive-phase music therapy was reported to be effective in the treatment and rehabilitation of several diseases. This study explored the effect of phase I cardiac rehabilitation combined with 5-phase music in acute myocardial infarction (AMI) patients after emergency percutaneous coronary intervention.MethodsThis prospective pilot study enrolled AMI patients who received percutaneous coronary intervention from the Traditional Chinese Medicine Hospital from July 2018 to December 2019. The participants were randomized in a 1:1:1 ratio to the control, cardiac rehabilitation, and rehabilitation-music groups. The primary endpoint was the hospital anxiety and depression scale. The secondary endpoints were the myocardial infarction dimensional assessment scale, self-rating sleep status, 6-minute walk test, and left ventricular ejection fraction.ResultsThe study included 150 AMI patients (n = 50/group). Hospital anxiety and depression scale showed significant time effects for both anxiety and depression (both P < .05), a treatment effect for depression (P = .02), and an interaction effect for anxiety (P = .02). A time effect was also observed for diet, sleep disorders, 6-minute walk test, and left ventricular ejection fraction (all P < .001). A difference among groups was observed for emotional reaction (P = .001). Interactions effects were observed for diet (P = .01) and sleep disorders (P = .03).ConclusionPhase I cardiac rehabilitation combined with 5-phase music could alleviate anxiety and depression and improve sleep quality.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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