• Maha Hameed, Sakshi Prasad, Esha Jain, Bekir Nihat Dogrul, Ahmad Al-Oleimat, Bidushi Pokhrel, Selia Chowdhury, Edzel Lorraine Co, Saloni Mitra, Jonathan Quinonez, Samir Ruxmohan, and Joel Stein.
• Larkin Community Hospital, South Miami, FL, USA.
• Curr Pain Headache Rep. 2023 Apr 1; 27 (4): 576357-63.

Purpose Of ReviewCannabis has been used since ancient times for medical and recreational research. This review article will document the validity of how medical cannabis can be utilized for chronic nonmalignant pain management.Recent FindingsCurrent cannabis research has shown that medical cannabis is indicated for symptom management for many conditions not limited to cancer, chronic pain, headaches, migraines, and psychological disorders (anxiety and post-traumatic stress disorder). Δ9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) are active ingredients in cannabis that modulate a patient's symptoms. These compounds work to decrease nociception and symptom frequency via the endocannabinoid system. Research regarding pain management is limited within the USA as the Drug Enforcement Agency (DEA) classifies it as a schedule one drug. Few studies have found a limited relationship between chronic pain and medical cannabis use. A total of 77 articles were selected after a thorough screening process using PubMed and Google Scholar. This paper demonstrates that medical cannabis use provides adequate pain management. Patients suffering from chronic nonmalignant pain may benefit from medical cannabis due to its convenience and efficacy.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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