• Internal medicine · Oct 2023

    Case Reports

    Idiopathic Intracranial Hypertension with Disproportionately Enlarged Subarachnoid Space Hydrocephalus on Imaging: A Case Report.

    • Ken Kunugitani, Satoshi Miura, Masanori Sawamura, Koki Mitani, Masakazu Okawa, Naohiro Egawa, and Ryosuke Takahashi.
    • Integrated Clinical Education Center, Kyoto University Hospital, Japan.
    • Intern. Med. 2023 Oct 15; 62 (20): 304330463043-3046.

    AbstractThe pathophysiology of idiopathic intracranial hypertension (IIH) and idiopathic normal-pressure hydrocephalus (iNPH) differs in terms of cerebrospinal fluid (CSF) pressure and imaging-related characteristics. A 51-year-old man presented with optic nerve papillary edema, visual disturbance, bilateral abducens nerve palsy, and a wide-based gait. Imaging showed characteristic findings of IIH and disproportionately enlarged subarachnoid space hydrocephalus (DESH) - characteristic of iNPH. A CSF examination revealed marked CSF hypertension. IIH with iNPH-like imaging features (DESH) was diagnosed, and ventriculoperitoneal shunt surgery was performed. Postoperatively, the visual acuity and visual field improved. This report also describes the distinct and overlapping pathophysiological mechanisms of IIH and iNPH.

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