• World Neurosurg · May 2023

    Outcomes after microvascular decompression for sole arterial versus venous compression in trigeminal neuralgia.

    • Sumil K Nair, Michael E Xie, Kathleen Ran, Anita Kalluri, Collin Kilgore, Judy Huang, Michael Lim, Chetan Bettegowda, and Risheng Xu.
    • Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    • World Neurosurg. 2023 May 1; 173: e542e547e542-e547.

    ObjectiveIn most cases of trigeminal neuralgia (TN), the trigeminal nerve is compressed by the arterial vasculature. We sought to address the gap in understanding of pain outcomes in patients with sole arterial versus sole venous compression.MethodsWe retrospectively reviewed all patients undergoing microvascular decompression at our institution, identifying patients with either sole arterial or venous compression. We dichotomized patients into arterial or venous groups and obtained demographics and postoperative complications for each case. Barrow Neurological Index (BNI) pain scores were collected preoperatively, postoperatively, and at final follow-up, as well as recurrence of pain. Differences were calculated via χ2 tests t tests, and Mann-Whitney U Tests. Ordinal regression was used to account for variables known to influence TN pain. Kaplan-Meier analysis was used to determine recurrence-free survival.ResultsOf 1044 patients, 642 (61.5%) had either sole arterial or venous compression. Of these cases, 472 showed arterial compression and 170 showed sole venous compression. Patients in the venous compression group were significantly younger (P < 0.001). Patients with sole venous compression showed worse preoperative (P = 0.04) and final follow-up (P < 0.001) pain scores. Patients with sole venous compression had significantly higher rate of pain recurrence (P = 0.02) and BNI score at pain recurrence (P = 0.04). On ordinal regression, venous compression was found to independently predict worse BNI pain scores (odds ratio, 1.66; P = 0.003). Kaplan-Meier analysis showed a significant relationship between sole venous compression and increased risk of pain recurrence (P = 0.03).ConclusionsPatients with TN with sole venous compression show worse pain outcomes after microvascular decompression compared with those with only arterial compression.Copyright © 2023 Elsevier Inc. All rights reserved.

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