• Tetsuya Hara, Akiko Ozawa, Koh Shibutani, Kayoko Tsujino, Yasushi Miyauchi, Takashi Kawano, Kenji Ito, Hirokazu Sakai, Miyuki Yokota, and Working Group for the Preparation of Practical Guidelines for Safe Sedation, Safety Committee of the Japanese Society of Anesthesiologists.
• Department of Anesthesiology and Intensive Care Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, Nagasaki, 852-8501, Japan. tetsuya@nagasaki-u.ac.jp.
• J Anesth. 2023 Jun 1; 37 (3): 340356340-356.

AbstractThis practical guide has been developed to ensure safe and effective sedation performed in adult patients outside of the operating room, for instance in intensive care units and dental treatment rooms and in the field of palliative care. Sedation levels are classified based on level of consciousness, airway reflex, spontaneous ventilation, and cardiovascular function. Deep sedation induces loss of consciousness and protective reflexes, and can cause respiratory depression and pulmonary aspiration. Invasive medical procedures necessitating deep sedation include cardiac ablation, endoscopic submucosal dissection, and internal radiation therapy. Appropriate analgesia is necessary for procedures that require deep sedation. The sedationist should evaluate the risks of the planned procedure, explain the sedation process to the patient, and obtain the patient's informed consent. Major parameters to be evaluated preoperatively are the patient's airway and general condition. Equipment, instruments, and drugs necessary for emergency situations should be defined and routinely maintained. To prevent aspiration, patients scheduled for moderate or deep sedation should fast preoperatively. In both inpatients and outpatients, biological monitoring should be continued until the discharge criteria are met. Anesthesiologists should be involved in management systems that ensure safe and effective sedation even if they do not personally perform all sedation procedures.© 2023. The Author(s) under exclusive licence to Japanese Society of Anesthesiologists.

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