• Wu Ding, Zaiwei Fan, Yuehuai Xu, Chunshou Wei, Zhian Li, Yingli Lin, Jianming Zhu, and Guodong Ruan.
• Department of Oncological Surgery, Shaoxing Second Hospital, Shaoxing, China.
• Medicine (Baltimore). 2023 Mar 10; 102 (10): e33146e33146.

BackgroundMagnetic resonance imaging (MRI) is more accurate than mammography in screening for breast cancer. Exposure to ionizing radiation from repeated diagnostic X-rays may be a cause of breast cancer.MethodsWe conducted systematic searches on PubMed, Cochrane and Embase to identify studies on women who underwent mammography or MRI screening. A meta-analysis was performed to compare the detection rate of breast cancer by mammography, MRI or both.ResultsA total of 18 diagnostic publications were identified and included in the meta-analysis. Among the 1000 screened women, MRI alone increased the detection rate of breast cancer by 8 compared with mammography alone (RR 0.48, 95% CI 0.42-0.54), and MRI plus mammography increased the detection rate of breast cancer by 1 compared with MRI alone (RR 0.86, 95% CI 0.78-0.96). Subgroup analysis demonstrated that the diagnostic efficacy of MRI plus mammography in breast was obviously better than that of MRI alone or mammography alone.ConclusionsScreening with MRI alone might be the best choice for women at high risk of breast cancer.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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