• Zhaohui Liu, Runhua Lin, Ruinuan Wu, Jiwen Deng, and Dayong Sun.
• The Department of Gastroenterology, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, China.
• Medicine (Baltimore). 2023 Mar 10; 102 (10): e33215e33215.

RationaleThe traditional methods for exchanging the endoscopic nasobiliary drainage (ENBD) tube from the mouth to the nose, such as the guidewire method, sponge holding forceps method, and finger method, have significant drawbacks including pharyngeal stimulation symptoms, high incidence of epistaxis, low success rate, and potential bite injuries to the operator.Patient ConcernsA case series of 9 patients who underwent ENBD at Shenzhen Second People's Hospital from January 2021 to December 2021 was collected.DiagnosesThe study included 9 patients diagnosed with choledocholithiasis, with 3 males and 6 females, with an average age of (55 ± 9.798) years (range 43-71).InterventionsThe M-NED was used to exchange the ENBD tube, and the success rate, operation time, and complications were recorded.OutcomesAll patients successfully completed the operation in one go with an average mouth-nose exchange time of (44.67 ± 13.388) seconds (range 28-65). Two patients had mild adverse events, one of which was controllable bleeding caused by nasal mucosal injury with an estimated blood loss of 1 mL. The other patient had nausea during the operation, which improved after completion.LessonsThe novel M-NED is an effective and safe method for exchanging the ENBD tube from the mouth to the nose with a high success rate and low incidence of complications. It is a device with potential clinical application value.Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc.

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