• Transplant. Proc. · Jun 2005

    Randomized Controlled Trial Comparative Study Clinical Trial

    A randomized study comparing combined spinal epidural or general anesthesia for renal transplant surgery.

    • N Hadimioglu, Z Ertug, Z Bigat, M Yilmaz, and A Yegin.
    • Department of Anesthesiology, Akdeniz University, Dumlupinar Bulvari, Antalya 07050, Turkey.
    • Transplant. Proc. 2005 Jun 1;37(5):2020-2.

    IntroductionThe appropriate anesthesia for renal transplantation requires minimal toxicity for patients and for the transplanted organ, as well as sufficient pain relief and maintenance of vital functions. The aim of this study was to determine how the anesthetic technique influences the outcome in patients after renal transplantation in terms of preoperative and intraoperative hemodynamic changes and blood gas changes.MethodsFifty adult patients undergoing renal transplantation were randomly divided into two groups receiving standardized general anesthesia or combined spinal and epidural anesthesia.ResultsDemographically both groups were similar. Total anesthesia time (202 +/- 53 vs 186 +/- 37 minutes) and surgical time (191 +/- 52 vs 162 +/- 31 minutes) did not differ between the groups. The heart rate and systolic blood pressure values of the groups as measured before induction and 5, 15, 20, 30, as well as 60 minutes thereafter did not differ between the groups. Neither the frequency of bradycardia (four vs two) nor of hypotension (six vs four) during anesthesia differed between regional versus general anesthesia groups.ConclusionRegional is an important alternative to general anesthesia during renal transplantation surgery in adult patients.

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