• Gac Med Mex · Jan 2023

    Effect of probiotics on glucose levels and weight gain in mice exposed to low doses of malathion.

    • Marco A Simoni-Berra, Jorge A Yáñez-Santos, Jorge A Girón-Ortiz, Manuel Huerta-Lara, and María L Cedillo-Ramírez.
    • Environmental Sciences Postgraduate Program.
    • Gac Med Mex. 2023 Jan 1; 159 (1): 444844-48.

    IntroductionOwing to its ability to reduce the toxicity of environmental pollutants that are risk factors for diabetes and obesity, the use of probiotic bacteria might aid the treatment of these diseases.ObjectiveTo determine the effects of chronic exposure to low-dose malathion on weight and glucose levels in mice, as well as to evaluate the protective role of a probiotic supplement.MethodsWeight and serum glucose levels of four groups of mice (control, malathion-exposed [10 ppm], probiotics and malathion + probiotics) were determined every 10 days for 180 days.ResultsMalathion administration induced an increase in weight and glucose levels in the malathion group mice in comparison with the other groups.ConclusionsConsumption of food contaminated with malathion residues increases glucose levels and favors weight gain, while consumption of probiotics reduces the effects generated by residues in food.Copyright: © 2023 Permanyer.

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