• María Del C Jiménez-González, Berenice Mejía-Aguirre, and Iván de J Ascencio-Montiel.
• High Specialty Medical Unit, Cardiology Hospital, Centro Médico Nacional Siglo XXI.
• Gac Med Mex. 2023 Jan 1; 159 (1): 172317-23.

IntroductionMediastinitis after cardiovascular surgery gives rise to prolonged hospital stay and increased medical care costs, and is associated with high in-hospital mortality.ObjectiveTo describe the clinical characteristics of patients with post-surgical mediastinitis, including the isolated microorganisms, resistance profile, and in-hospital survival.MethodsCross-sectional study of patients with bacteriologically-confirmed post-surgical mediastinitis cared for at a cardiology hospital in Mexico City between January 2017 and March 2019.ResultsFifty-eight cases of mediastinitis were included. Median age was 67 years. Most subjects were males who underwent myocardial revascularization. During in-hospital follow-up, all-cause and mediastinitis-related mortality were 27.6% and 20.7%, respectively. Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli were the most commonly isolated microorganisms. High resistance to methicillin was found in coagulase-negative staphylococci, as well as high expression of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae strains.ConclusionsHigh mortality and significant antimicrobial resistance were found in patients with post-cardiac surgery mediastinitis.Copyright: © 2023 Permanyer.

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