• Internal medicine · Nov 2023

    Granulocyte Colony-stimulating Factor-associated Aortitis on Gallium Scintigraphy.

    • Haruka Ozaki, Kohji Takemura, Rika Kizawa, Takeshi Yamaguchi, Chinatsu Komiyama, Masato Tachi, Hirotaka Maruno, Yuko Tanabe, Koichi Suyama, and Yuji Miura.
    • Department of Medical Oncology, Toranomon Hospital, Japan.
    • Intern. Med. 2023 Nov 1; 62 (21): 316331663163-3166.

    AbstractAortitis is a rare adverse event associated with granulocyte colony-stimulating factor (G-CSF). Contrast-enhanced computed tomography (CECT) is widely used to diagnose G-CSF-associated aortitis. However, the usefulness of gallium scintigraphy for the diagnosis of G-CSF-associated aortitis is unknown. We herein report a set of pre- and post-treatment gallium scintigrams of a patient with G-CSF-associated aortitis. During the diagnosis, gallium scintigraphy revealed hot spots on the arterial walls that appeared inflamed on CECT. Both the CECT and gallium scintigraphy findings disappeared. Gallium scintigraphy can be a supportive diagnostic tool for G-CSF-associated aortitis, especially in patients with an impaired renal function or allergy to iodine contrast.

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