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Case Reports
Improper Application of a Rivastigmine Patch to the Back of the Neck Induced Toxic Symptoms.
- Kosuke Matsuzono, Yoshinori Mita, Goro Imai, and Shigeru Fujimoto.
- Division of Neurology, Department of Medicine, Jichi Medical University, Japan.
- Intern. Med. 2023 Nov 1; 62 (21): 324732503247-3250.
AbstractRivastigmine is a highly effective drug for treating Alzheimer's disease. However, its addiction can be fatal, so proper use of this transdermal drug is needed. We herein report an 85-year-old woman with Alzheimer's disease who inappropriately placed rivastigmine patches on the back of her neck. She suffered from acute cholinergic syndrome, hypersalivation, anorexia, dyspnea, and vomiting. These symptoms disappeared when the improper use of rivastigmine patches was ceased. This case serves as a warning to physicians and pharmacists of the risk associated with the improper placement of rivastigmine patches.
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