• Jeffrey B Ware and Danielle K Sandsmark.
• Department of Radiology, Neuroradiology Division, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: Jeffrey.Ware2@pennmedicine.upenn.edu.
• Neuroimaging Clin. N. Am. 2023 May 1; 33 (2): 261269261-269.

AbstractThe acute and long-term neurobiological sequelae of concussion (mild traumatic brain injury [mTBI]) and sub-concussive head trauma have become increasingly apparent in recent decades in part due to neuroimaging research. Although imaging has an established role in the clinical management of mTBI for the identification of intracranial lesions warranting urgent interventions, MR imaging is increasingly employed for the detection of post-traumatic sequelae which carry important prognostic significance. As neuroimaging research continues to elucidate the pathophysiology of TBI underlying prolonged recovery and the development of persistent post-concussive symptoms, there is a strong motivation to translate these techniques into clinical use for improved diagnosis and therapeutic monitoring.Copyright © 2023 Elsevier Inc. All rights reserved.

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